Rolapitant, CAS [[552292-08-7]]

Produktübersicht

• Artikelname: Rolapitant, CAS [[552292-08-7]]
• Artikelnummer: TGM-T3716
• Hersteller Artikelnummer: T3716
• Alternativnummer: TGM-T3716-1MLX10MM(INDMSO),TGM-T3716-1MG,TGM-T3716-2MG,TGM-T3716-5MG,TGM-T3716-10MG,TGM-T3716-25MG,TGM-T3716-50MG,TGM-T3716-100MG,TGM-T3716-500MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: SCH619734

Produktbeschreibung

Rolapitant (SCH619734) Hydrochloride is the hydrochloride salt form of rolapitant, an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. Upon oral administration, rolapitant competitively binds to and blocks the activity of the NK1-receptor in the central nervous system, thereby inhibiting the binding of the endogenous ligand, substance P (SP). This may prevent both SP-induced emesis and chemotherapy-induced nausea and vomiting (CINV). The interaction of SP with the NK1-receptor plays a key role in the induction of nausea and vomiting caused by emetogenic cancer chemotherapy. Compared to other NK1-receptor antagonists, rolapitant has both a more rapid onset of action and a much longer half-life.

Produkteigenschaften

• Molekulargewicht: 500.48
• Reinheit: 99.86%
• CAS Nummer: [552292-08-7]
• Formel: C25H26F6N2O2
• Target-Kategorie: Neurokinin receptor

Bilder

T3716