Tryptoquivaline D is a fungal metabolite found in [Neosartorya siamensis] with noted anticancer activity. It induces nuclear chromatin condensation, a marker of apoptosis, in HCT116 colon and HepG2 liver cancer cells at a concentration of 150 µM. Tryptoquivaline D (1-100 µM), alone or with doxorubicin, reduces the viability of A549 lung cancer cells.
Molekulargewicht:
532.553
CAS Nummer:
[60676-56-4]
Formel:
C28H28N4O7
Target-Kategorie:
Others
T37584
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