P11149, a derivative of Galanthamine, acts as a competitive, orally active, and selective AChE inhibitor with the ability to weakly penetrate the blood-brain barrier (BBB). It demonstrates selective inhibition, exhibiting an IC50 of 1.3 µM for rat BChE/AChE, and shows central cholinergic activity, behavioral efficacy, and safety. P11149 is utilized in Alzheimers disease research[1].
Molekulargewicht:
472.02
CAS Nummer:
[164724-79-2]
Formel:
C27H34ClNO4
Target-Kategorie:
Cholinesterase (ChE)|||Others
T38005
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