Herquline A is an alkaloid fungal metabolite originally isolated from P. herquei. It inhibits cell death induced by influenza A strain A/PR/8/34 in MDCK cells with an IC50 value of 10 µg/ml and inhibits viral replication in a plaque assay in a concentration-dependent manner. Herquline A also inhibits platelet aggregation induced by ADP and platelet-activating factor (PAF) in vitro (IC50s = 180 and 240 µM, respectively).
Molekulargewicht:
314.429
CAS Nummer:
[71812-08-3]
Formel:
C19H26N2O2
Target-Kategorie:
Others|||Influenza Virus
T38015
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