(R)-KT109 is the (R) isomer of the diacylglycerol lipase beta (DAGLbeta) inhibitor KT109 . (R)-KT109 is an inhibitor of DAGLbeta (IC50 = 0.79 nM) and of DAGLalpha-mediated hydrolysis of 1-stearoyl-2-arachidonoyl-sn-glycerol . It also inhibits alpha/beta-hydrolase domain-containing protein 6 (ABHD6) with an IC50 value of 2.51 nM. (R)-KT109 is more potent at DAGLbeta, DAGLalpha, and ABHD6 than (S)-KT109 .
Molekulargewicht:
422.52
CAS Nummer:
[2055172-60-4]
Formel:
C27H26N4O
Target-Kategorie:
Others
T38031
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