3-sulfo Galactosylsphingosine (ammonium salt), CAS [[1246681-32-2]] Preis auf Anfrage
Artikelnummer:
TGM-T38090
Hersteller Artikelnummer:
T38090
Alternativnummer:
TGM-T38090-1MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
3-sulfo Galactosylsphingosine is a form of sulfatide that is lacking the fatty acyl group. It decreases migration and adhesion of B35 neuroblastoma cells and increases cell rounding when used at a concentration of 20 µM. It also inhibits PKC and cytochrome c oxidase activity when used at concentrations of 150 and 50-100 µM, respectively. 3-sulfo Galactosylsphingosine accumulates in patients with metachromatic leukodystrophy, a lysosomal storage disorder characterized by arylsulfatase A (ASA) deficiency leading to progressive demyelination and neuromotor deficits. In mice lacking ASA, levels of 3-sulfo galactosylsphingosine increase after one month of age followed by demyelination and neuromotor deficits. 3-sulfo Galactosylsphingosine has been used as a standard for the quantification of 3-sulfo galactosylsphingosine by LC-MS.
Molekulargewicht:
558.73
CAS Nummer:
[1246681-32-2]
Formel:
C24H50N2O10S
Target-Kategorie:
Others|||Phospholipase
T38090
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