3-sulfo Galactosylsphingosine (ammonium salt), CAS [[1246681-32-2]] Preis auf Anfrage

Artikelnummer: TGM-T38090
Artikelname: 3-sulfo Galactosylsphingosine (ammonium salt), CAS [[1246681-32-2]] Preis auf Anfrage
Artikelnummer: TGM-T38090
Hersteller Artikelnummer: T38090
Alternativnummer: TGM-T38090-1MG
Hersteller: TargetMol
Kategorie: Biochemikalien
3-sulfo Galactosylsphingosine is a form of sulfatide that is lacking the fatty acyl group. It decreases migration and adhesion of B35 neuroblastoma cells and increases cell rounding when used at a concentration of 20 µM. It also inhibits PKC and cytochrome c oxidase activity when used at concentrations of 150 and 50-100 µM, respectively. 3-sulfo Galactosylsphingosine accumulates in patients with metachromatic leukodystrophy, a lysosomal storage disorder characterized by arylsulfatase A (ASA) deficiency leading to progressive demyelination and neuromotor deficits. In mice lacking ASA, levels of 3-sulfo galactosylsphingosine increase after one month of age followed by demyelination and neuromotor deficits. 3-sulfo Galactosylsphingosine has been used as a standard for the quantification of 3-sulfo galactosylsphingosine by LC-MS.
Molekulargewicht: 558.73
CAS Nummer: [1246681-32-2]
Formel: C24H50N2O10S
Target-Kategorie: Others|||Phospholipase
T38090