Germicidin A is a pyranone originally derived from S. viridochromogenes that acts as a reversible, autoregulative inhibitor of spore germination and hyphal elongation in the genus Streptomyces at concentrations as low as 200 pM. During germination, spores of Streptomyces excrete germicidin A along with other germicidin homologs, which inhibit germination of its own arthrospores. At higher concentrations, germicidin A can inhibit the porcine Na+/K+-activated ATPase (ID50 = 100 µM) and prevent the germination of the cress L. sativum.
Molekulargewicht:
196.24
CAS Nummer:
[151271-57-7]
Formel:
C11H16O3
Target-Kategorie:
Others
T38151
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