STING agonist 12b is an agonist of stimulator of interferon genes (STING).1It binds to STING (Kd= 26.4 µM) and induces interferon reporter gene expression in cells expressing human or mouse STING (EC50s = 7.45 and 10.23 µM, respectively). STING agonist 12b (40 µM) induces expression of TNF-a, IL-6, IP-10, and IL-1b in THP-1 cells.
Molekulargewicht:
253.3
CAS Nummer:
[2411100-70-2]
Formel:
C16H15NO2
Target-Kategorie:
Others|||STING
T38159
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