STING Agonist C11, CAS [[875863-22-2]]

Produktübersicht

• Artikelname: STING Agonist C11, CAS [[875863-22-2]]
• Artikelnummer: TGM-T38161
• Hersteller Artikelnummer: T38161
• Alternativnummer: TGM-T38161-1MG, TGM-T38161-5MG, TGM-T38161-10MG, TGM-T38161-500UG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: STING Agonist C11

Produktbeschreibung

STING agonist C11 is an agonist of the stimulator of interferon genes (STING) pathway.1 It induces secretion of type I IFN from THF and MM6 cells when used at a concentration of 50 µM. STING agonist C11 induces phosphorylation of IFN regulatory factor 3 (IRF3) and increases expression of IFIT1 and viperin, but not IL-1beta, IL-6, or IL-8 in THF cells in a STING-dependent manner. It reduces viral titers of chikungunya, Venezuelan equine encephalitis, onyong-nyong, Mayaro, and Ross River viruses grown in THF cells (EC90s = 16.44, 16.7, 18.84, 25.19, and 22.57 µM, respectively), an effect that is dependent on the presence of STING and the IFN-alpha/beta receptor (IFNAR).

Produkteigenschaften

• Molekulargewicht: 382.44
• CAS Nummer: [875863-22-2]
• Formel: C19H18N4O3S
• Target-Kategorie: Others|||STING

Bilder

T38161