Mpro inhibitor N3 hemihydrate is a potent antagonist of the SARS-CoV-2 main protease (Mpro), with an EC50 of 16.77 µM against SARS-CoV-2. It specifically inhibits Mpro in various coronaviruses, including SARS-CoV, MERS-CoV, HCoV-229E (IC50 4.0 µM), FIPV (IC50 8.8 µM), and MHV-A59 (IC50 2.7 µM) [1][2].
Target-Kategorie:
Others|||Virus Protease|||SARS-CoV
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