PAQ is a neuroprotective agent. It protects dopaminergic neurons from cell death without inhibiting glial cell proliferation in a rat midbrain culture model of Parkinsons disease when used at a concentration of 10 µM. PAQ (25 or 50 mg/kg, twice per day) prevents loss of dopaminergic neurons in the substantia nigra in a mouse model of Parkinsons disease induced by MPTP.
Molekulargewicht:
221.26
CAS Nummer:
[943902-10-1]
Formel:
C14H11N3
Target-Kategorie:
Others|||Calcium Channel
T38202
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