Polygalasaponin F, CAS [[882664-74-6]]

Produktübersicht

• Artikelname: Polygalasaponin F, CAS [[882664-74-6]]
• Artikelnummer: TGM-T3826
• Hersteller Artikelnummer: T3826
• Alternativnummer: TGM-T3826-1MLX10MM(INDMSO),TGM-T3826-2MG,TGM-T3826-5MG,TGM-T3826-10MG,TGM-T3826-25MG,TGM-T3826-50MG,TGM-T3826-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

Polygalasaponin F has anti-neuroinflammatory activity, can inhibit the release of inflammatory cytokines TNF-alpha and NO induced by lipopolysaccharides (LPS) and reduce the expression of inducible nitric oxide synthases. Polygalasaponin F can significantly inhibit the cytotoxicity of conditioned medium prepared by LPS-stimulated BV-2 microglia (LPS conditioned media) to neuronal PC12 cells and improve cell viability. Polygalasaponin F can induce long-term potentiation in hippocampal dentate gyrus in anesthetized rats via NMDAR activation mediated by Ca(2+)/calmodulin-dependent kinase II, extracellular signal-regulated kinase and cAMP response element-binding protein signaling pathway. PS-F inhibits the secretions of neuroinflammatory cytokines by the regulation of the NF-kB-signaling pathway.

Produkteigenschaften

• Molekulargewicht: 1091.24
• Reinheit: 98.00%
• CAS Nummer: [882664-74-6]
• Formel: C53H86O23
• Target-Kategorie: PI3K|||Akt|||TLR|||NF-kappaB

Bilder

T3826