PSMalpha3 is a peptide compound that can be utilized to induce tolerance in dendritic cells (DCs) for DC vaccination strategies. It effectively penetrates and modulates human monocyte-derived DCs by modifying the maturation process induced by TLR2 or TLR4. Additionally, PSMalpha3 inhibits the production of both pro- and anti-inflammatory cytokines and decreases antigen uptake. Notably, PSMalpha3 is a significant virulence factor released by the most pathogenic strains of methicillin-resistant Staphylococcus aureus (MRSA).
Molekulargewicht:
2635.17
CAS Nummer:
[1001405-52-2]
Formel:
C128H192N28O30S
Target-Kategorie:
Others|||TLR
T38394
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