RTIL 13 is a highly effective inhibitor of dynamin GTPase, exhibiting an IC50 value of 2.3 µM for dynamin I GTPase. Furthermore, it selectively interacts with the pleckstrin homology lipid binding domain. This compound effectively suppresses both receptor-mediated and synaptic vesicle endocytosis, demonstrating IC50 values of 9.3 µM and 7.1 µM, respectively.
Molekulargewicht:
571.685
CAS Nummer:
[1009376-10-6]
Formel:
C30H55BrN2O3
Target-Kategorie:
Others|||Ras
T38407
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