HG-7-85-01 is a novel ATP-competitive and type II tyrosine kinase inhibitor targeting both wild-type and watchman mutant BCR-ABL, PDGFRalpha, Kit, and Src kinases, with inhibitory effects on the proliferation of a variety of cancer cell lines, leading to G0/G1-phase blockade and apoptosis induction in BCR-ABL-expressing cells.
Molekulargewicht:
608.68
Reinheit:
98.08%
CAS Nummer:
[1258391-13-7]
Formel:
C31H31F3N6O2S
Target-Kategorie:
Apoptosis|||JAK|||PDGFR|||c-Kit|||Src|||Bcr-Abl
T38653
T38653
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