S65487 (VOB560) hydrochloride, a potent and selective Bcl-2 inhibitor, is effective against BCL-2 mutations, including G101V and D103Y, while exhibiting poor affinity for MCL-1, BFL-1, and BCL-XL. This compound induces apoptosis and possesses anticancer activities.
Molekulargewicht:
753.73
CAS Nummer:
[1644543-95-2]
Formel:
C41H42Cl2N6O4
Target-Kategorie:
Others|||Apoptosis|||Bcl-2 Family
T39135
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