DS86760016 is a highly effective inhibitor of leucyl-tRNA synthetase (LeuRS), demonstrating potent activity against multidrug-resistant (MDR) Gram-negative bacteria including Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa. Notably, DS86760016 effectively inhibits LeuRS enzymes derived from Escherichia coli, Pseudomonas aeruginosa, and Acinetobacter baumannii, exhibiting IC50 values of 0.38 µM, 0.62 µM, and 0.16 µM, respectively.
Molekulargewicht:
243.45
CAS Nummer:
[1853176-89-2]
Formel:
C9H11BClNO4
Target-Kategorie:
Antibacterial|||Others
T39296
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