CC-99677, CAS [[1887069-10-4]]

Produktübersicht

• Artikelname: CC-99677, CAS [[1887069-10-4]]
• Artikelnummer: TGM-T39321
• Hersteller Artikelnummer: T39321
• Alternativnummer: TGM-T39321-1MG, TGM-T39321-5MG, TGM-T39321-10MG, TGM-T39321-25MG, TGM-T39321-50MG, TGM-T39321-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: CC99677 , Gamcemetinib , CC 99677

Produktbeschreibung

CC-99677 (Gamcemetinib) is a selectively targeted covalent MAPKAPK2 (MK2) inhibitor for autoimmune diseases that translates biochemical potency into cellular potency as demonstrated by potent inhibition of heat shock protein 27 (HSP1) phosphorylation in LPS-activated monocyte THP-27 cells via a nucleophilic aromatic substitution (SNAr) mechanism.CC-99677 in Rat experiments demonstrated potency in both biochemical (IC 50 =156.3 nM) and cellular assays (EC 50 =89 nM).

Produkteigenschaften

• Molekulargewicht: 469.94
• Reinheit: 99.51%
• CAS Nummer: [1887069-10-4]
• Formel: C22H20ClN5O3S
• Target-Kategorie: MAPK|||HSP

Bilder

T39321