TH5427 hydrochloride, CAS [[2253744-57-7]]

Artikelnummer: TGM-T39785
Artikelname: TH5427 hydrochloride, CAS [[2253744-57-7]]
Artikelnummer: TGM-T39785
Hersteller Artikelnummer: T39785
Alternativnummer: TGM-T39785-10MG
Hersteller: TargetMol
Kategorie: Biochemikalien
TH5427 hydrochloride is a potent and selective inhibitor of NUDT5 with an IC50 of 29 nM. It demonstrates a remarkable 690-fold selectivity towards NUDT5 compared to MTH1. Moreover, TH5427 hydrochloride effectively inhibits progestin-dependent, PAR-derived nuclear ATP synthesis in breast cancer cells, thereby impeding chromatin remodeling, gene regulation, and ultimately suppressing proliferation.
Molekulargewicht: 527.79
CAS Nummer: [2253744-57-7]
Formel: C20H21Cl3N8O3
Target-Kategorie: Others|||DNA/RNA Synthesis
T39785