5-Hydroxymethyl-2-deoxycytidine is an oxidized derivative of 5-methyl-2-deoxycytidine (5-mdC) in DNA, causing DNA damage reactions, chromosomal aberrations, replication fork damage, and loss of cell viability.5-Hydroxymethyl-2-deoxycytidine is an oxidized derivative of 5-methyl-2-deoxycytidine in DNA. Hydroxymethyl-2-deoxycytidine replication fork instability is associated with the presence of poly(ADP-ribose) polymerase 1 (PARP1) on chromatin.
Molekulargewicht:
257.24
Reinheit:
99.80%
CAS Nummer:
[7226-77-9]
Formel:
C10H15N3O5
Target-Kategorie:
PARP|||DNA/RNA Synthesis
T40834
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