CBL0137, CAS [[1197996-80-7]]

Produktübersicht

• Artikelname: CBL0137, CAS [[1197996-80-7]]
• Artikelnummer: TGM-T4126
• Hersteller Artikelnummer: T4126
• Alternativnummer: TGM-T4126-1MLX10MM(INDMSO),TGM-T4126-1MG,TGM-T4126-5MG,TGM-T4126-10MG,TGM-T4126-25MG,TGM-T4126-50MG,TGM-T4126-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: Curaxin 137 , CBLC137

Produktbeschreibung

CBL0137 (Curaxin 137), a metabolically stable curaxin, activates p53 (EC50: 0.37 µM) and inhibits NF-kappaB (EC50: 0.47 µM). It functionally inactivates the facilitates chromatin transcription complex (FACT), driving the effects on p53 and NF-kappaB and promoting cancer cell death. CBL0137 has broad anticancer activity in mice when administered orally, eradicates drug-resistant cancer stem cells, and potentiates the efficacy of gemcitabine in preClinicalal models of pancreatic cancer.

Produkteigenschaften

• Molekulargewicht: 336.43
• Reinheit: 98.00%
• CAS Nummer: [1197996-80-7]
• Formel: C21H24N2O2
• Target-Kategorie: Histone Acetyltransferase|||NF-kappaB|||MDM-2/p53|||p53

Bilder

T4126