PF-04753299 is a potent and selective inhibitor of UDP-3-O-(R-3-hydroxymyristol)-N-acetylglucosamine deacetylase (LpxC), demonstrating bactericidal effects against gonococcal isolates and exhibiting inhibitory activity against E. coli, P. aeruginosa, and K. pneumoniae, with minimum inhibitory concentration (MIC) 90 values of 2 µg/ml, 4 µg/ml, and 16 µg/ml, respectively. This compound is utilized in researching gram-negative bacterial infections [1].
Molekulargewicht:
347.43
Reinheit:
99.63%
CAS Nummer:
[1289620-49-0]
Formel:
C18H21NO4S
Target-Kategorie:
Others|||Antibacterial
T41275
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