Proguanil hydrochloride, CAS [[637-32-1]]

Produktübersicht

• Artikelname: Proguanil hydrochloride, CAS [[637-32-1]]
• Artikelnummer: TGM-T4382
• Hersteller Artikelnummer: T4382
• Alternativnummer: TGM-T4382-1MLX10MM(INDMSO), TGM-T4382-10MG, TGM-T4382-25MG, TGM-T4382-50MG, TGM-T4382-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: Paludrine hydrochloride , Chlorguanide hydrochloride , Chloroquanil

Produktbeschreibung

Proguanil hydrochloride (Chloroquanil) is a biguanide compound which metabolizes in the body to form cycloguanil, an anti-malaria agent.Upon hydrolysis, Proguanil hydrochloride is converted to its active cyclic triazine metabolite, cycloguanil, by a cytochrome P450 dependent reaction. Cycloguanil selectively inhibits the bifunctional dihydrofolate reductase-thymidylate synthase of plasmodium parasite, thereby disrupting deoxythymidylate synthesis and ultimately blocking DNA and protein synthesis in the parasite.

Produkteigenschaften

• Molekulargewicht: 290.19
• Reinheit: 99.03%
• CAS Nummer: [637-32-1]
• Formel: C11H17Cl2N5
• Target-Kategorie: Dehydrogenase|||Parasite|||DNA/RNA Synthesis|||Antifolate