RO1138452, CAS [[221529-58-4]]

Produktübersicht

• Artikelname: RO1138452, CAS [[221529-58-4]]
• Artikelnummer: TGM-T4436
• Hersteller Artikelnummer: T4436
• Alternativnummer: TGM-T4436-1MLX10MM(INDMSO),TGM-T4436-1MG,TGM-T4436-2MG,TGM-T4436-5MG,TGM-T4436-10MG,TGM-T4436-25MG,TGM-T4436-50MG,TGM-T4436-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: CAY10441

Produktbeschreibung

RO1138452 (CAY10441) is a selective and orally bioavailable antagonist of prostacyclin receptor (pKi: 8.3). It antagonizes the carbaprostacyclin-induced activation of human neuroblastoma adenylate cyclase, blocking cyclic AMP accumulation in a dose-dependent manner. Likewise, it inhibits the binding of tritiated iloprost to rodent neuroblastoma cells with a Ki of about 1.5 nM. At levels between 2-20 mg/kg in rats, CAY10441 shows significant analgesic activity in standard antinociceptive assays [1].

Produkteigenschaften

• Molekulargewicht: 309.41
• Reinheit: 95.73%
• CAS Nummer: [221529-58-4]
• Formel: C19H23N3O
• Target-Kategorie: Prostaglandin Receptor

Bilder

T4436