NS309, CAS [[18711-16-5]]

Produktübersicht

• Artikelname: NS309, CAS [[18711-16-5]]
• Artikelnummer: TGM-T4612
• Hersteller Artikelnummer: T4612
• Alternativnummer: TGM-T4612-1MLX10MM(INDMSO),TGM-T4612-5MG,TGM-T4612-10MG,TGM-T4612-25MG,TGM-T4612-50MG,TGM-T4612-100MG,TGM-T4612-200MG,TGM-T4612-500MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

NS309 is a nonselective activator of small- and intermediate-conductance Ca2+-activated K+ (SK/KCa2 and IK/KCa3.1) channels (EC50s range from 0.12-1.2 µM for SK channels and 10-90 nM for IK channels). It can also activate voltage-gated Kv11.1 channels (hERG, IC50 = 1 µM), but does not, however, affect large conductance (BK/KCa1.1) channels. NS309 can modulate neuronal firing patterns by enhancing SK-mediated hyperpolarizing effects. It is 730-fold (SK channels) and 7,400-fold (IK channels) more potent than 1-EBIO and often used in conjunction with CyPPA to distinguish between SK1 and SK3 subtypes.

Produkteigenschaften

• Molekulargewicht: 231.04
• Reinheit: 0.9755
• CAS Nummer: [18711-16-5]
• Formel: C8H4Cl2N2O2
• Target-Kategorie: Potassium Channel|||EGFR

Bilder

T4612