1. Isofraxidin (Phytodolor) protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner. 2. Isofraxidin has a protective effect against LPS-induced ALI, and the protective effect of Isofraxidin seems to result from the inhibition of COX-2 protein expression in the lung, which regulates the production of PGE2. 3. Isofraxidin possesses significant analgesic and anti-inflammatory activities that may be mediated through the regulation of pro-inflammatory cytokines, TNF-alpha and the phosphorylation of p38 and ERK1/2.
Molekulargewicht:
222.19
Reinheit:
95%
CAS Nummer:
[486-21-5]
Formel:
C11H10O5
Target-Kategorie:
TLR|||MMP|||ERK|||p38 MAPK|||COX
T5S0045
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