Neferine, CAS [[2292-16-2]]

Produktübersicht

• Artikelname: Neferine, CAS [[2292-16-2]]
• Artikelnummer: TGM-T5S1097
• Hersteller Artikelnummer: T5S1097
• Alternativnummer: TGM-T5S1097-1MLX10MM(INDMSO),TGM-T5S1097-5MG,TGM-T5S1097-10MG,TGM-T5S1097-25MG,TGM-T5S1097-50MG,TGM-T5S1097-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: (R)-1,2-Dimethoxyaporphine , (-)-Neferine

Produktbeschreibung

1. Neferine ((-)-Neferine) has anti-tumor activities , Metabolic activation mediated by CYP3A4 and GSH depletion enhanced Neferine-induced cytotoxicity. 2. Neferine can be helpful to increase the efficacy of DOX and to achieve anticancer synergism by curbing the toxicity. 3. Neferine inhibited high glucose-induced endothelial apoptosis via blocking ROS/Akt/NF-kappaB pathway, which provides the evidence for using Neferine to treat diabetic vasculopathy. 4. Neferine induced apoptosis in a dose-dependent manner with the hypergeneration of reactive oxygen species, activation of MAPKs, lipid peroxidation, depletion of cellular antioxidant pool, loss of mitochondrial membrane potential, and intracellular calcium accumulation.

Produkteigenschaften

• Molekulargewicht: 624.77
• Reinheit: 98.81%
• CAS Nummer: [2292-16-2]
• Formel: C38H44N2O6
• Target-Kategorie: Autophagy|||Apoptosis|||NF-kappaB

Bilder

T5S1097