Nutlin-3a, CAS [[675576-98-4]]
Artikelnummer:
TGM-T6023
- Bilder (1)
| Artikelname: | Nutlin-3a, CAS [[675576-98-4]] |
| Artikelnummer: | TGM-T6023 |
| Hersteller Artikelnummer: | T6023 |
| Alternativnummer: | TGM-T6023-1MLX10MM(INDMSO), TGM-T6023-1MG, TGM-T6023-2MG, TGM-T6023-5MG, TGM-T6023-10MG, TGM-T6023-25MG, TGM-T6023-50MG, TGM-T6023-100MG |
| Hersteller: | TargetMol |
| Kategorie: | Biochemikalien |
| Alternative Synonym: | (-)-Nutlin-3 , Nutlin-3a chiral , (-)-Nutlin-3 |
| Nutlin-3a is the active enantiomer of Nutlin-3, an MDM2 antagonist that inhibits MDM2-p53 interaction (Ki=90 nM) and activates p53. Nutlin-3a binds preferentially to the p53-binding pocket of MDM2, leading to stabilization of p53 and activation of the p53 pathway. Nutlin-3a has antitumor activity. |
| Molekulargewicht: | 581.49 |
| Reinheit: | 95.62% |
| CAS Nummer: | [675576-98-4] |
| Formel: | C30H30Cl2N4O4 |
| Target-Kategorie: | MDM-2/p53|||Apoptosis|||Autophagy|||E1/E2/E3 Enzyme |

