Mirin is a Mre11-Rad50-Nbs1 (MRN) complex inhibitor that inhibits MRN-dependent ATM activation without affecting ATM protein kinase activity. It also inhibits Mre11-associated exonuclease activity, thereby disrupting DNA double-strand break repair.Mirin induces cell cycle arrest in G1 phase.
Molekulargewicht:
220.25
Reinheit:
99.24%
CAS Nummer:
[299953-00-7]
Formel:
C10H8N2O2S
Target-Kategorie:
ATM/ATR
T60273
T60273
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