PKN1/2-IN-1 is a potent and selective PKN2 inhibitor with 14-fold higher selectivity for PKN2 than PKN1, membrane permeability and anticancer potential.Protein kinase N proteins (PKN1, PKN2 and PKN3) are effectors of Rho GTPases and are critical for survival in several tumor cell lines including prostate and breast cancer.
Molekulargewicht:
241.29
Reinheit:
99.72%
CAS Nummer:
[942425-34-5]
Formel:
C14H15N3O
Target-Kategorie:
PKC|||Others
T60339
T60339
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