Glucocerebrosidase-IN-1 (compound 11a) is a potent and selective GCase (glucocerebrosidase) inhibitor, with an IC50 of 29.3 µM and a Ki of 18.5 µM. Due to GCase involvement in pathological disorders consequent to enzyme deficiency, Glucocerebrosidase-IN-1 can be used for research of Gaucher disease (GD) and Parkinsons disease (PD)[1].
Molekulargewicht:
245.36
CAS Nummer:
[2279945-76-3]
Formel:
C13H27NO3
Target-Kategorie:
Others|||Glucosidase|||glycosidase
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