LSD1/2-IN-4, a derivative of PCPA, functions as an inhibitor for both lysine-specific demethylase 1 (LSD1) and lysine-specific demethylase 2 (LSD2), demonstrating K i values of 0.11 µM and 130 µM against LSD1 and LSD2, respectively. This compound is utilized in researching various cancers, notably T-cell acute lymphoblastic leukemia (TALL) [1].
Molekulargewicht:
248.07
Formel:
C9H8BrF2N
Target-Kategorie:
Histone Demethylase|||Others
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