Nrf2-ARE/hMAO-B/QR2 modulator 1, a resveratrol derivative and multi-target-directed ligand (mtdl), activated the NRF2-ARE pathway (CD = 9.83 µM), selectively inhibited hMAO-B and QR2(quinone reductase-2,NQO2) (IC 50 = 8.05 and 0.57 µM), and was able to promote hippocampal neurogenesis and exert neuroprotective and antioxidant effects in an Alzheimers disease model.
Molekulargewicht:
256.26
Reinheit:
98.50%
CAS Nummer:
[3035124-25-2]
Formel:
C14H12N2O3
Target-Kategorie:
Monoamine Oxidase|||Nrf2|||ROS|||MAO|||NADPH|||Reactive Oxygen Species
T60395
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