Tubulin inhibitor 14 is a potent inhibitor of NQO2 (quinone oxidoreductase 2) with an IC50 of 1.0 µM, which also inhibits tubulin polymerization and the formation of endothelial cell capillary-like tubes. As a microtubule destabilizer, Tubulin inhibitor 14 has potential tumor-selective, anti-angiogenic, and vascular-destructive properties [1].
Molekulargewicht:
257.23
Formel:
C15H9F2NO
Target-Kategorie:
Others|||Apoptosis|||Microtubule Associated
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