Nepicastat (SYN117) is a selective, potent, and orally active dopamine-beta-hydroxylase inhibitor capable of crossing the blood-brain barrier (BBB), producing concentration-dependent inhibition of bovine and human dopamine-beta-hydroxylase with IC50s of 8.5 nM and 9 nM [1] [2] [3].
Molekulargewicht:
295.35
CAS Nummer:
[173997-05-2]
Formel:
C14H15F2N3S
Target-Kategorie:
Others|||Hydroxylase
T60633
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