(R)-STU104 is a novel TAK1-MKK3 protein-protein interaction (PPI) inhibitor that inhibits TNF-alpha and suppresses the TAK1/MKK3/p38/MnK1/MK2/elF4E signalling pathway by binding to MKK3 and disrupting TAK1 phosphorylation of MKK3. (R)-STU104 is a candidate compound for the treatment of ulcerative colitis.
Molekulargewicht:
298.33
Reinheit:
99.42%
CAS Nummer:
[2767124-77-4]
Formel:
C18H18O4
Target-Kategorie:
p38 MAPK|||MAPK|||TNF
T60657
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