B-Raf IN 8 (compound 7g) is a potent inhibitor of B-Raf (IC50 = 70.65 nM) with antitumor activity, demonstrating IC50 values of 9.78, 13.78, 18.52, and 29.85 µM against hepatocellular carcinoma (HEPG-2), colon carcinoma (HCT-116), mammary gland (MCF-7), and human prostate cancer (PC-3) cells [1].
Molekulargewicht:
307.35
CAS Nummer:
[1215313-19-1]
Formel:
C18H17N3O2
Target-Kategorie:
Others|||Raf
T60727
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