ENMD-1068 hydrochloride, a selective protease-activated receptor 2 (PAR2) antagonist, inhibits TGF-beta1/Smad signaling, thereby reducing hepatic stellate cell activation and collagen expression. It also suppresses the proliferation of endometrial cells and triggers apoptosis in epithelial lesion cells. This compound is utilized in researching endometriosis and liver fibrosis [1] [2].
Molekulargewicht:
319.87
CAS Nummer:
[2703451-51-6]
Formel:
C15H30ClN3O2
Target-Kategorie:
Others|||Apoptosis|||Protease-activated Receptor
T60854
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