Verosudil (AR-12286) is a highly potent Rho kinase (ROCK) inhibitor with a Ki of 2 nM and 2 nM against ROCK1 and ROCK2, respectively. AR-12286 mitigates steroid-induced intraocular pressure in mice by decreasing intraocular pressure through enhanced outflow of aqueous humor via the trabecular meshwork.
Molekulargewicht:
327.4
Reinheit:
99.72%
CAS Nummer:
[1414854-42-4]
Formel:
C17H17N3O2S
Target-Kategorie:
ROCK
T60924
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