MurB-IN-1 (compound 44) is a potent inhibitor of MurB, an essential enzyme involved in the synthesis of the bacterial cell wall. With a binding affinity of Kd 3.57 µM, MurB-IN-1 effectively hinders MurB activity, presenting a promising therapeutic option against P. aeruginosa, a highly virulent and opportunistic pathogen associated with severe infections and mortality [1].
Molekulargewicht:
339.1
Formel:
C12H7Cl2F3N2O2
Target-Kategorie:
Others
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