KH-259 (compound 1) is a highly potent, selective, and CNS-penetrant HDAC6 inhibitor, with an IC50 of 0.26 µM, exerting antidepressant effects in mice by inhibiting HDAC6 within the brain and holding promise as a valuable tool for neurodegenerative diseases research [1].
Molekulargewicht:
339.43
Formel:
C20H25N3O2
Target-Kategorie:
Others|||HDAC
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