HDAC6-IN-3 (Compound 14) is a potent anti-prostate cancer agent that acts as an orally active inhibitor of HDAC6. It has IC50 values ranging from 0.02-1.54 µM for HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, and HDAC10. Additionally, HDAC6-IN-3 also demonstrates effective inhibition of MAO-A (IC50 = 0.79 µM) and LSD1 [1].
Molekulargewicht:
345.44
Formel:
C19H27N3O3
Target-Kategorie:
Others|||HDAC|||Histone Demethylase
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