hCAI/II-IN-2 (compound 2b) is a highly effective dual inhibitor of human carbonic anhydrase I and II (hCA I/II), with Ki values of 40.97 nM for hCA I, 15.15 nM for hCA II, and 61.88 nM for hCA IX. With its anti-hypoxic properties, hCAI/II-IN-2 demonstrates activity against acute mountain sickness (AMS) and exhibits low cellular activity [1].
Molekulargewicht:
356.38
CAS Nummer:
[2480283-75-6]
Formel:
C12H12N4O5S2
Target-Kategorie:
Others|||Carbonic Anhydrase
T61282
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