CYP121A1-IN-1 is a potent inhibitor of CYP121A1, demonstrating favorable activity against Mycobacterium tuberculosis (H37Rv MIC 90 ~6.25 µM, ~2.2 µg/mL). It significantly reduces mycocyclosin production by blocking the CYP121A1-mediated conversion of cyclo(l-tyrosyl-l-tyrosyl) to mycocyclosin [1].
Molekulargewicht:
356.42
Formel:
C22H20N4O
Target-Kategorie:
Cytochromes P450|||Others
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