LDHA/PDKs-IN-1 (compound 20e) is a highly effective dual inhibitor of PDKs and LDHA, with IC50 values of 0.8 µM and 0.15 µM, respectively. It significantly suppresses A549 cell proliferation (EC50 = 13.2 µM), reduces lactate formation, and enhances oxygen consumption, holding great promise for cancer research [1].
Molekulargewicht:
360.38
CAS Nummer:
[2490699-40-4]
Formel:
C19H21FN2O4
Target-Kategorie:
Others|||PDK
T61339
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