CXCR2 antagonist 3 (compound 11h) is a highly effective inhibitor of CXC chemokine receptor 2 (CXCR2), displaying double-digit nanomolar potencies in inhibiting neutrophil infiltration into the air pouch. Additionally, it reduces neutrophil and MDSC infiltration while enhancing CD3+ T lymphocyte infiltration into Pan02 tumor tissues [1].
Molekulargewicht:
362.38
CAS Nummer:
[2647464-92-2]
Formel:
C17H15FN2O4S
Target-Kategorie:
CXCR|||Others
T61356
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