Zolunicant (MM-110) is a potent nicotinic alpha3beta4 receptor inhibitor with an IC50 of 0.90 µM, showing promise in combating addiction. It effectively reduces self-administration of addictive agents such as morphine, cocaine, methamphetamine, nicotine, and ethanol in rat models, indicating its potential as a treatment for various forms of drug abuse [1]. Additionally, Zolunicant exhibits strong leishmanicidal activity against Leishmania amazonensis, expanding its therapeutic prospects [2].
Molekulargewicht:
368.47
CAS Nummer:
[188125-42-0]
Formel:
C22H28N2O3
Target-Kategorie:
Parasite|||AChR
T61452
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