MtTMPK-IN-5 (compound 17) is a highly effective inhibitor of M. tuberculosis thymidylate kinase (Mtb TMPK), demonstrating remarkable enzyme inhibitory activity with an IC50 of 34 µM. Additionally, MtTMPK-IN-5 exhibits notable activity against M. tuberculosis, with an MIC of 12.5 µM. Given its potent properties, MtTMPK-IN-5 serves as a valuable tool for tuberculosis research [1].
Molekulargewicht:
377.44
Formel:
C21H23N5O2
Target-Kategorie:
Others|||Antibacterial|||DNA/RNA Synthesis
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