ATR-IN-15 (compound 1) is a highly potent, orally active ATR kinase inhibitor with an IC50 of 8 nM. It also exhibits inhibitory activity against human colon tumor cells LoVo, DNA-PK, and PI3K, with IC50 values of 47, 663, and 5131 nM, respectively [1].
Molekulargewicht:
378.43
CAS Nummer:
[2756665-52-6]
Formel:
C19H22N8O
Target-Kategorie:
Others|||ATM/ATR|||DNA-PK|||PI3K
T61587
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