ATX inhibitor 15 (compound 30) is an indole-based carbamate derivative with a strong inhibitory effect on autotaxin (ATX), demonstrated by an IC50 of 2.17 nM. It effectively inhibits ATX activity in vivo, suppresses the expression of pro-fibrotic genes, and exhibits protective effects in Bleomycin-induced lung fibrosis in mice [1].
Molekulargewicht:
558.09
CAS Nummer:
[2484811-52-9]
Formel:
C27H32ClN5O4S
Target-Kategorie:
PDE|||Others
T61612
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